Porous conductive and biocompatible scaffolds on the basis of polycaprolactone and polythiophene for scaffolding

Raana Sarvari1 · Bakhshali Massoumi2 · Amir Zareh2 · Younes Beygi‑Khosrowshahi3 · Samira Agbolaghi3


The fabrication of novel scaffolds was represented on the basis of conductive and biodegradable copolymers. The star-like polycaprolactone (S-PCL) was synthesized from dipentaerythritol as a core by a catalyst of Sn(oct)8 through ring-opening technique. After functionalization of S-PCL by thiophene, thiophene monomer was polymerized from polycaprolactone ends via chemical oxidation polymerization to reach star-like polycaprolactone–polythiophene (S-PCL–PTh). The scaffolds demonstrated a porous configuration (160–۱۹۰ nm) having the great surface area as well as conductivity of 0.011 S cm−۱٫ The cytocompatibility measurements exhibited thatthe nanofibers were not toxic to the MG63 cells





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